Summary: Placenta Accreta Spectrum (PAS) disorders involve abnormal placental attachment to the uterine wall, categorized into placenta accreta, increta, and percreta. The rise in PAS cases correlates with increased cesarean deliveries and uterine …
AI is revolutionizing the early detection and diagnosis of gastrointestinal diseases through advanced machine learning and deep learning techniques. By analyzing vast datasets from medical imaging, AI systems, particularly convolutional neural …
Cystic fibrosis (CF) is a genetic disorder caused by mutations in the CFTR gene, leading to thick mucus accumulation in organs such as the lungs and pancreas. The most common mutation, F508del, affects primarily Caucasian populations. CF manifest as …
The article discusses the significant interconnection between type 2 diabetes (T2D) and coronary artery disease (CAD), highlighting that diabetes is a major risk factor for cardiovascular issues due to chronic hyperglycemia, insulin resistance, and …
The article emphasizes the significance of shared decision-making (SDM) in cardiovascular care, particularly in managing atherosclerotic cardiovascular disease (ASCVD). SDM fosters collaboration between healthcare professionals and patients, …
The article examines the eukaryotic diversity present in the gut microbiomes of wild baboons from the Amboseli ecosystem, highlighting the critical roles that fungi, protists, and helminths play. Using shotgun metagenomic sequencing, researchers …
Heat stress significantly impacts aerobic exercise performance, leading to fatigue, reduced endurance, and compromised cardiovascular function, especially in athletes participating in events lasting over 30 minutes. Physiological responses to heat …
The onset of type 2 diabetes (T2DM) is influenced by genetic, environmental, and lifestyle factors, with major behavioral risks identified by the World Health Organization (WHO) including obesity, physical inactivity, unhealthy diet, tobacco use, and …
The article “Overview of Nanomaterials in Cancer Therapy” discusses the innovative use of nanomaterials in cancer treatment, addressing the limitations of traditional therapies like chemotherapy and radiotherapy. Nanomaterials, which …
Chronic pain is a persistent condition that can arise from various sources, significantly affecting physical function and emotional well-being. It is influenced by biological, psychological, and social factors, indicating that it is more than just a …
The article discusses the significant role of grandparents in shaping children’s diets and physical activity patterns, especially in multi-generational households. It highlights that while grandparents can provide nurturing and support, their …
The article discusses the crucial role of hormones, particularly gonadotropin-releasing hormone (GnRH), in regulating avian reproduction, emphasizing the timing of life cycle events like migration and breeding in relation to environmental cues. …
The article discusses the significant role of dietary weight loss in reducing inflammation, particularly in individuals with obesity. A systematic review indicates that weight loss of at least 5% leads to notable decreases in inflammatory markers …
The article discusses the significant role of gut microbiota in the efficacy of metformin, a common medication for type 2 diabetes mellitus (T2DM). It highlights that metformin modifies gut microbiota composition by increasing beneficial bacteria …
The article emphasizes the critical importance of early diagnosis in dementia management, highlighting its benefits such as timely intervention, improved quality of life, and reduced caregiver burden. Biomarkers related to DNA methylation and machine …
The article explores the association between heavy metal exposure and stress urinary incontinence (SUI), emphasizing the growing concern of heavy metal contamination in the environment. A study analyzing NHANES data from 2013 to 2018 revealed that …
The article discusses the significance of nature in improving mental health, especially among urban youth who face challenges due to high population density and limited green spaces. Research shows that connection with nature can reduce anxiety and …
The article discusses the critical role of public transit in enhancing food accessibility in urban areas, particularly for low-income populations who may lack personal vehicles. It highlights that reliable public transit systems can connect residents …
The article discusses the significant disparities in diabetes prevalence and outcomes among Black and Hispanic adults compared to non-Hispanic White adults, highlighting that 12.1% of Black adults and 11.7% of Hispanic adults are diagnosed with …
The article discusses the significant disparities in diabetes prevalence and outcomes among marginalized populations, particularly Black and Hispanic communities in the U.S., where diabetes rates are notably higher than in white populations. The …
Phantom Earthquake Syndrome is a rare condition experienced by individuals who have survived significant earthquakes, characterized by false sensations of ground movement and symptoms such as dizziness, anxiety, and nausea. Patients often face …
Diabetic retinopathy (DR) is a significant global cause of blindness, particularly affecting working-age adults due to diabetes mellitus. It damages retinal blood vessels and can lead to vision impairment or blindness, with an estimated 422 million …
The article emphasizes the critical importance of early reproductive health education at the primary school level, highlighting how it helps children understand their bodies and the changes during puberty. Research shows that early education equips …
Acute Kidney Injury (AKI) is a serious condition affecting millions worldwide, characterized by a sudden decline in kidney function due to various causes, including medication toxicity and systemic diseases. It significantly impacts hospitalized …
The article discusses the significant impact of isotretinoin on corneal innervation and tear film stability, highlighting its potential to cause corneal nerve damage and reduced tear production. Studies using in vivo confocal microscopy (IVCM) reveal …
The article discusses the critical role of urate transporter 1 (URAT1) in hyperuricemia and insulin resistance, highlighting its regulation by insulin signaling which enhances urate reabsorption in the kidneys. Research by Fujii et al. (2025) …
Mucosal vaccines are designed to stimulate immune responses at mucosal surfaces, critical for preventing infections. Unlike traditional injectable vaccines, mucosal vaccines can generate localized immune responses, potentially combating cancer by …
The article discusses the innovative use of chitosan-based microneedles for delivering Amphotericin B (AmB) in the treatment of fungal keratitis (FK), a serious condition that can lead to blindness. Traditional treatment methods face challenges due …
The article discusses the environmental impact of berry by-products, particularly pomace, which can make up 25-50% of the total berry weight. Improper disposal of these by-products poses health risks and increases waste management costs. However, …
The article discusses the critical role of copper in cancer cell growth and metabolism, particularly in glioblastoma (GBM). Elevated copper levels are linked to tumor progression, promoting tumor cell proliferation through key signaling pathways. A …
The article discusses the importance of micronutrients—vitamins and minerals—for maintaining periodontal health. Key micronutrients include vitamins A, C, D, E, K, and essential minerals like calcium, magnesium, and zinc. Deficiencies in these …
The article discusses the significant impact of type 2 diabetes (T2D) on cognitive health, highlighting the increased risk of dementia and cognitive impairments in individuals with diabetes. Chronic hyperglycemia is linked to cognitive decline …
The article discusses the resurgence of interest in traditional medicine, particularly ethnomedicine, during the COVID-19 pandemic, focusing on Gorontalo Province, Indonesia. Local communities have historically used a variety of plants to treat …
The article explores the transformative role of computer vision technology in agriculture, particularly for detecting vegetable diseases that threaten crop yields. Computer vision utilizes camera systems and algorithms to automate disease detection, …
The article discusses the bidirectional relationship between gastroesophageal reflux disease (GERD) and bipolar disorder, highlighting that each condition can increase the risk of the other. It presents an odds ratio indicating a significant …
The article discusses the mechanisms of resistance in triple-negative breast cancer (TNBC) and their implications for treatment strategies. Key resistance mechanisms include the presence of cancer stem cells (CSCs), which possess self-renewal …
Phosphorus is essential for brain function and health, playing a vital role in neuronal activity, cellular integrity, and energy metabolism through ATP production. Hypophosphatemia, a condition characterized by low phosphate levels, affects around …
The article discusses Post-Acute Sequelae of SARS-CoV-2 (PASC), highlighting its common symptoms such as fatigue, cognitive impairment, neurological issues, cardiovascular symptoms, and psychological effects. It emphasizes the potential of Dual …
The cGAS-STING pathway is crucial for the innate immune response, detecting cytosolic DNA and activating type I interferon responses, which are vital in fighting tumors. Despite the potential of STING pathway activation in cancer immunotherapy, …
The article summarizes recent findings on genetic risk factors for frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) and the clinical applications of venous sinus stenting. It identifies significant common and rare genetic variants …
Dendritic cell (DC) vaccines are a promising approach in cancer immunotherapy, leveraging the role of dendritic cells in bridging innate and adaptive immune responses to stimulate anti-tumor immunity. However, their clinical efficacy is challenged by …
Asherman’s syndrome (AS) is a condition marked by intrauterine adhesions that can lead to infertility, pelvic pain, and menstrual irregularities. It affects 1-5% of women undergoing infertility treatments, especially those with a history of …
The article discusses the transformative role of Artificial Intelligence (AI) in rheumatology imaging, highlighting its ability to enhance diagnostic capabilities through efficient analysis of complex imaging datasets. AI algorithms, leveraging …
The article discusses the significant impact of cognitive-behavioral factors on the development and persistence of temporomandibular disorders (TMD). It highlights that individuals with high levels of anxiety, stress, and pain catastrophizing are …
The article discusses the innovative fabrication techniques for cobalt-doped hafnia films, essential for enhancing their structural and electrocatalytic properties, particularly in glucose sensing applications. The films are synthesized using …
Antibiotic resistance (AMR) is a critical global health issue, linked to over 1.14 million deaths annually, with rising concerns particularly in Saudi Arabia due to increasing cases of resistant bacteria. The overuse and misuse of antibiotics are …
Gambling disorder (GD) has become a significant concern due to its rising prevalence linked to increased gambling opportunities. It is recognized by the American Psychiatric Association as a non-substance addiction, often associated with severe …
Ginsenoside Rd (GSRd) is a bioactive compound derived from ginseng, showing potential in treating various neurological disorders such as ischemic stroke, spinal cord injury (SCI), Alzheimer’s disease (AD), and Parkinson’s disease (PD). In …
The article discusses the molecular changes induced by radiation therapy (RT) on skin and muscle recovery, highlighting key genes affected, such as COL4A5 and KRT17. Post-radiation, the skin can experience fibrosis and altered texture, while muscles, …
The article emphasizes the critical role of dietary management in chronic kidney disease (CKD) treatment, focusing on controlling risk factors like hypertension, diabetes, and hyperlipidemia. Key nutritional guidelines for CKD patients include …
The article discusses the growing popularity of gummies as an alternative to traditional medication forms like tablets and capsules, particularly beneficial for pediatric patients who have difficulty swallowing pills. It highlights recent …
Combined Pituitary Hormone Deficiency (CPHD) is a rare endocrine disorder resulting from genetic mutations, particularly in the POU1F1 gene, which affects pituitary hormone production. This deficiency can lead to growth hormone (GH), …
The article discusses the effects of hormonal contraceptives (HCs), particularly oral contraceptives (OCs), on metabolic health, highlighting their widespread use among women in the U.S. While OCs are effective in preventing pregnancy, they may lead …
Iceberg lettuce (Lactuca sativa var. capitata) is vital for global food security due to its nutritional value and economic significance. Its crisp texture and mild flavor make it a popular choice in home cooking and fast food. Major producers include …
The article discusses the significance of patient satisfaction in primary healthcare, emphasizing its correlation with health outcomes. A study from King Abdulaziz Medical City highlights that communication quality, service accessibility, and the …
The article discusses the use of biocompatible nanocomposites, specifically the Ba–Ce–Cu ferrite/TiO2 nanocomposite, as an effective and environmentally friendly solution for controlling terrestrial gastropods like Monacha cartusiana, which are …
The article emphasizes the significance of active aging measurement in health care, particularly for older adults, using tools like the UJACAS questionnaire to assess health determinants and tailor interventions for better health outcomes. It also …
The article discusses the significant barriers faced by transgender and gender nonconforming (TGNC) adults in accessing healthcare, based on a study of 116 participants. Key barriers include: 1. Acceptability Issues: Discrimination and misgendering …
The article emphasizes the critical role of diet quality in preventing non-communicable diseases (NCDs) in Nigeria, where the rise of conditions like obesity, diabetes, and hypertension is linked to changing dietary habits influenced by urbanization …
Radiation-induced trismus is a significant complication in head and neck cancer patients, affecting 30% to 60% of those undergoing radiation therapy. It is characterized by restricted mouth opening, which impairs eating, speaking, and oral hygiene. …
Ferroptosis is a regulated form of cell death characterized by iron-dependent accumulation of reactive oxygen species (ROS) and lipid peroxidation, making it particularly relevant in cancer therapy. Cancer cells often rely heavily on iron, creating a …
Cladosporium infections in birds can manifest with various clinical signs, including skin lesions, respiratory distress, and behavioral changes. A study indicated that Cladosporium was prevalent in yellow-throated buntings’ mycelia-like skin crusts. …
The article emphasizes the critical importance of quick access to Automated External Defibrillators (AEDs) during cardiac arrest situations, highlighting that survival chances decrease by 7% to 10% with each minute that passes without defibrillation. …
High-protein diets are gaining popularity for their benefits in weight loss and body composition improvement. Research shows that individuals on high-protein diets experience reduced body fat and increased lean body mass. For example, mice on a 50% …
Arthritis is a widespread condition affecting over 350 million people globally, primarily osteoarthritis and rheumatoid arthritis. It causes joint inflammation, pain, and stiffness, leading to chronic disability and economic burdens on healthcare …
The article discusses the symptoms of depression in patients with epilepsy (PWE), highlighting that these symptoms can differ from those in the general population. Common symptoms include persistent sadness, loss of interest in activities, appetite …
The article explores the health benefits of ferulic acid, particularly for post-menopausal women, highlighting its potential to alleviate symptoms such as hot flashes and skin dryness due to estrogen deficiency. Studies show that ferulic acid, …
This article explores several cutting-edge studies on iron regulation and clinical therapies. In the first section, researchers reveal how plants optimize iron uptake by integrating light signals with nutrient acquisition. Key elements include the …
The article provides an in-depth review of the evolution of peer review and academic publishing, emphasizing the shift from society-based journals to a profit-driven model dominated by commercial publishers. It highlights critical issues such as …
Workplace health promotion (WHP) initiatives are crucial for enhancing employee well-being and organizational success. Defined by the World Health Organization, WHP encompasses coordinated activities aimed at improving health through individual and …
The article discusses the significant impact of nurse-managed care on hypertension management, revealing that patients in such settings show better adherence to lifestyle counseling guidelines compared to those without nurse involvement. It …
Early goals of care conversations in the ICU are essential for understanding patient preferences and improving outcomes, such as shorter ICU stays and better alignment with patient wishes. Research, including the SUPPORT trial, reveals that many …
The article discusses the significance of TOM40, a key oncogene in Oral Squamous Cell Carcinoma (OSCC), which is a prevalent and aggressive form of head and neck cancer. TOM40 is crucial for mitochondrial function and is linked to increased tumor …
Long Covid, or post-acute sequelae of SARS-CoV-2 infection (PASC), refers to lingering symptoms that can persist for weeks or months after a COVID-19 infection, affecting nearly 20% of patients. Common symptoms include fatigue, brain fog, shortness …
Testosterone Replacement Therapy (TRT) is designed for men with low testosterone levels, essential for muscle mass, bone density, and mood. Diagnosis involves blood tests confirming low levels, with symptoms including fatigue and decreased libido. …
