Table of Contents
The Impact of Race-Based Stress on Cardiometabolic Health
Recent studies indicate that psychosocial stressors, particularly those associated with race and discrimination, significantly contribute to CMD among African American women. Stressful life events, including experiences of racism, have been shown to exacerbate inflammatory responses and increase the risk of chronic diseases (Schwartz et al., 2025). Research has demonstrated that women who encounter high levels of racial stress may experience elevated markers of inflammation, such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) (Schwartz et al., 2025).
Race-based stress affects not only mental health but also physiological health, leading to chronic conditions such as obesity and hypertension. African American women, who often navigate the dual challenges of sexism and racism, report higher levels of psychological distress, which may further escalate their risk for CMD (Schwartz et al., 2025). Understanding these dynamics is crucial for developing targeted interventions.
Key Symptoms and Risks Associated with Cardiometabolic Disease
Cardiometabolic disease encompasses a range of health conditions, including obesity, diabetes, and hypertension, which collectively increase the risk for cardiovascular events. Key symptoms to monitor in African American women include:
- Obesity: Defined as a body mass index (BMI) of 30 or higher, obesity is linked to increased inflammation and heart disease risk. Approximately 55% of non-Hispanic Black women are classified as obese (Schwartz et al., 2025).
- Hypertension: High blood pressure affects 43% of African American women, significantly raising the risk for heart disease and stroke (Schwartz et al., 2025).
- Diabetes: The prevalence of diabetes among African American women is concerning, with rates reaching 13% (Schwartz et al., 2025).
These conditions are often interrelated, creating a cycle of health decline that requires comprehensive management strategies.
Resilience, Stress, and Ethnicity: A Novel Intervention
To address the unique stressors that contribute to CMD, the Resilience, Stress, and Ethnicity (RiSE) program was developed. This intervention is designed specifically for African American women and focuses on enhancing resilience through a combination of cognitive behavioral strategies and stress reduction techniques.
The RiSE program consists of eight weekly group sessions that facilitate discussions around the impact of racism and promote adaptive coping strategies (Schwartz et al., 2025). Key components of the program include:
- Psychoeducation: Participants learn about the physiological effects of stress and how to manage their responses to discrimination.
- Skill Building: Techniques such as mindfulness and cognitive restructuring are taught to help participants develop adaptive coping mechanisms.
- Empowerment: The program encourages participants to share their experiences and support one another, fostering a community of resilience.
By integrating these elements, the RiSE program aims to lower stress-related symptoms and inflammation, ultimately reducing the incidence of CMD.
Measuring the Effectiveness of the RiSE Program
The effectiveness of the RiSE intervention will be evaluated through a randomized controlled trial, comparing participants’ stress-related symptoms and inflammatory markers before and after the intervention. Key metrics include:
- Salivary Inflammatory Biomarkers: Changes in levels of IL-6, TNF-α, and C-reactive protein (CRP) will be monitored to assess the physiological impact of the intervention.
- Psychosocial Assessments: Participants will complete validated surveys measuring perceived stress, depressive symptoms, and coping strategies at multiple time points throughout the study.
Preliminary results are promising, suggesting that the RiSE program may effectively mitigate stress-related symptoms in African American women at risk for CMD (Schwartz et al., 2025).
Future Directions for Cardiometabolic Health Interventions
As the understanding of CMD among African American women evolves, future interventions should focus on:
- Culturally Tailored Approaches: Continued development of programs that address the unique experiences and challenges faced by African American women is essential for improving health outcomes.
- Community Engagement: Collaborating with community leaders and organizations can enhance the reach and effectiveness of interventions.
- Longitudinal Studies: Future research should investigate the long-term effects of stress reduction interventions on CMD risk and overall health.
By focusing on these areas, we can better support African American women in achieving healthier lives and reducing the burden of cardiometabolic disease.
FAQ
What is cardiometabolic disease?
Cardiometabolic disease refers to a cluster of conditions, including obesity, hypertension, and diabetes, that increase the risk for cardiovascular disease and other health complications.
How does race-based stress affect health?
Race-based stress can lead to chronic inflammation, which contributes to the development of cardiometabolic diseases. It can also exacerbate mental health issues, further impacting overall well-being.
What is the RiSE program?
The RiSE (Resilience, Stress, and Ethnicity) program is an intervention designed for African American women that focuses on enhancing resilience through stress management and cognitive behavioral strategies.
How can I participate in the RiSE program?
The RiSE program is currently being tested in a randomized controlled trial. Interested participants can contact the research team for more information regarding eligibility and enrollment.
What are the potential benefits of participating in the RiSE program?
Participants may experience reductions in stress-related symptoms, improved coping strategies, and lower levels of inflammation, contributing to better overall health outcomes.
References
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Schwartz, A., Leung, T., Laborde, D., Saban, K. L. R. N., Joyce, C., Nyembwe, A., Janusek, L., Tell, D., de la Pena, P., Motley, D., Shawahin, L., Prescott, L., Potts-Thompson, S., & Taylor, J. Y. (2025). The Effectiveness of a Race-Based Stress Reduction Intervention on Improving Stress-Related Symptoms and Inflammation in African American Women at Risk for Cardiometabolic Disease: Protocol for Recruitment and Intervention for a Randomized Controlled Trial. JMIR Research Protocols. https://doi.org/10.2196/65649
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