Table of Contents
Overview of Orofacial Pain Related to COVID-19
The COVID-19 pandemic has significantly influenced various aspects of health, one of which is orofacial pain. Orofacial pain encompasses a range of conditions affecting the mouth, jaws, and face, which can manifest as toothaches, jaw pain, or neuralgias. Research indicates that the incidence of orofacial pain has notably increased since the onset of the pandemic, with a reported rise from 42.26% to 46.52% in affected individuals post-COVID-19 infection (Zhuang et al., 2024). Various factors, including the psychosocial impact of the pandemic, changes in healthcare access, and the direct effects of the virus on the body, contribute to this phenomenon.
Key Symptoms and Incidences of Orofacial Pain Post-Infection
Post-COVID-19, many patients report new or aggravated orofacial pain symptoms. According to a cross-sectional study conducted in Fujian Province, China, 14.22% of individuals developed “COVID-19 infection with orofacial pain” (CIOP) (Zhuang et al., 2024). Common symptoms include:
- Facial pain: Increased from 4.52% before infection to 8.64% post-infection.
- Oral mucosal pain: Rose from 10.74% to 13.24%.
- Temporomandibular joint (TMJ) pain: Reported aggravation in severity post-infection (VAS score increased from 2.40 to 3.08).
These findings suggest a direct correlation between COVID-19 infection and the exacerbation of orofacial pain conditions.
Symptom | Before Infection | After Infection | P-Value |
---|---|---|---|
Facial Pain | 4.52% | 8.64% | < 0.001 |
Oral Mucosal Pain | 10.74% | 13.24% | < 0.001 |
TMJ Pain (VAS Score) | 2.40 | 3.08 | 0.02 |
Risk Factors Influencing the Severity of Orofacial Pain
Several factors have been identified as influencing the severity of orofacial pain in patients recovering from COVID-19. Research indicates that male patients are more likely to experience aggravated symptoms (OR = 1.761, P < 0.001) (Zhuang et al., 2024). Other notable risk factors include:
- Number of COVID-19 symptoms: Individuals with a higher number of symptoms were more likely to report CIOP (OR = 1.494, P < 0.001).
- Preference for beverages: Patients who consumed tea or coffee showed lower incidences of CIOP (OR = 0.610, P = 0.003).
Understanding these factors is crucial for predicting which patients may require more intensive management of their orofacial pain.
Healthcare-Seeking Behavior Among Patients with Orofacial Pain
The pandemic has also altered healthcare-seeking behavior among individuals suffering from orofacial pain. Many patients expressed concerns about seeking treatment due to fears of COVID-19 transmission in dental settings. The study found that factors such as education level, income, and psychological state influenced patients’ willingness to seek care. Women were more likely to seek medical attention when less worried about COVID-19 transmission (OR = 0.749, P = 0.03) (Zhuang et al., 2024).
Factors Affecting Healthcare-Seeking Behavior
Factor | Odds Ratio (OR) | P-Value |
---|---|---|
Male Gender | 1.761 | < 0.001 |
Number of COVID-19 Symptoms | 1.494 | < 0.001 |
Drinking Tea or Coffee | 0.610 | 0.003 |
Education Level | 1.687 | < 0.001 |
Income Level | 1.796 | < 0.001 |
Worry about COVID-19 Transmission | 0.639 | 0.001 |
Recommendations for Managing Orofacial Pain During a Pandemic
To effectively manage orofacial pain during the ongoing COVID-19 pandemic, several recommendations can be made:
- Telehealth Services: Enhance the use of telemedicine for consultations to alleviate patient fears about in-person visits.
- Education: Provide clear communication regarding the safety measures in dental offices to encourage care-seeking behavior.
- Screening and Follow-Up: Implement routine screening for orofacial pain in individuals recovering from COVID-19, particularly those with risk factors.
- Multidisciplinary Approach: Encourage collaboration between dentists, primary care physicians, and mental health professionals to address the holistic needs of patients.
Conclusion
The COVID-19 pandemic has profoundly impacted the incidence and management of orofacial pain. As healthcare systems adapt to the new normal, understanding the characteristics and risk factors associated with CIOP will be vital in tailoring effective treatment strategies. Increased awareness and proactive healthcare-seeking behavior can mitigate the adverse effects of orofacial pain on patients’ quality of life.
FAQs
What is orofacial pain?
Orofacial pain refers to pain in the mouth, jaws, and face, which can include conditions like toothaches, jaw pain, and facial pain.
How has COVID-19 affected orofacial pain?
Studies have shown increased incidences of orofacial pain symptoms post-COVID-19 infection, with a notable rise in conditions like facial pain and TMJ pain.
What factors influence the severity of orofacial pain after COVID-19?
Factors include gender, the number of COVID-19 symptoms experienced, and personal habits such as beverage preferences.
How can healthcare providers improve care for patients with orofacial pain during the pandemic?
Providers can enhance telehealth services, educate patients on safety protocols, implement routine screenings, and adopt a multidisciplinary approach to care.
References
- Zhuang, S., Li, H., Lin, Y., Huang, M., Zhang, W., & Zhang, C. (2024). The Effect of COVID-19 Infection on Orofacial Pain: A Cross-sectional Study. https://doi.org/10.1016/j.identj.2024.07.007
- Takahashi, K. (2025). Community-based pathogen-specific incidence of influenza-like illness due to respiratory viruses in South-central Vietnam in 2009–2012: after a pandemic of influenza A viruses. https://doi.org/10.1186/s41182-025-00711-x
- Kuzi, S., Duygu, F., & Sencan, I. (2025). Investigation of Influenza Cases and Risk Factors Associated with Fatality in Türkiye. https://doi.org/10.14744/SEMB.2024.64614
- The Lactulose Breath Test Can Predict Refractory Gastroesophageal Reflux Disease by Measuring Bacterial Overgrowth in the Small Intestine. (2025). https://pubmed.ncbi.nlm.nih.gov/11974629/
- Severe Neutropenia Due to Carbimazole and the Importance of Early Recognition and Management. (2025). https://doi.org/10.7759/cureus.81867
- A comparison of pulmonary function pre and post mild SARS-CoV-2 infection among healthy adults. (2025). https://doi.org/10.1186/s12890-025-03613-0