Bone regeneration is an essential focus in tissue engineering, particularly for patients with bone loss due to injuries, tumors, or diseases. Traditional repair methods like autografts have limitations, prompting research into advanced biomaterials …
Periodontitis is a chronic inflammatory disease affecting the supporting structures of teeth, leading to significant dental issues and systemic health concerns. Traditional treatments face challenges, including antibiotic resistance and high …
The article discusses how 3D printing technology is transforming oral drug delivery systems, particularly for central nervous system (CNS) disorders. Traditional manufacturing often fails to meet the complex needs of patients, but 3D printing allows …
Osteoarthritis (OA) is a degenerative joint disease impacting millions globally, particularly affecting individuals over 60 years old. It leads to chronic pain, stiffness, and functional impairment, significantly reducing quality of life. The disease …
Intervertebral disc degeneration (IVDD) is a prevalent condition that affects many individuals, leading to significant lower back pain. Characterized by the deterioration of intervertebral discs, IVDD results in reduced disc height and changes in …
The article discusses the significance of water sorption in dental composites, emphasizing its impact on material longevity and mechanical properties. Water sorption, defined as the diffusion of water molecules into the composite’s polymer …
The article discusses the transformative impact of 3D printing technology on the pharmaceutical industry, specifically in creating customized medications tailored to individual patient needs. It highlights three primary 3D printing techniques: Fused …
Copper is a vital trace element that significantly contributes to bone health through collagen synthesis, osteoblast proliferation, and bone metabolism regulation. It also has antimicrobial properties that help prevent infections related to bone …
Knee osteoarthritis (KOA) is a common degenerative joint disease that leads to pain, stiffness, and decreased mobility, significantly affecting the quality of life, particularly in the elderly. Traditional treatments include non-steroidal …
The article discusses dental caries, a chronic infectious disease caused by the demineralization of tooth enamel due to acids produced by bacteria, particularly Streptococcus mutans. This bacterium thrives in acidic environments created by high sugar …
The article discusses the significant role of mitogen-activated protein kinase (MAPK) signaling pathways, particularly ERK1/2 and p38 MAPK, in the osteogenic differentiation of periodontal ligament stem cells (PDLSCs). These pathways are activated by …
The article discusses the growing popularity of gummies as an alternative to traditional medication forms like tablets and capsules, particularly beneficial for pediatric patients who have difficulty swallowing pills. It highlights recent …
Epidermal stem cells (EpSCs) are essential for skin maintenance and repair, residing in the epidermis and hair follicles. They proliferate and differentiate into keratinocytes during wound healing. Research shows that 1α,25-Dihydroxyvitamin D3 (VD3), …
The article discusses the transformative impact of 3D printing technology in the treatment of diabetic foot ulcers (DFUs). 3D printing enables the creation of customized wound dressings and assistive devices tailored to individual patient needs, …
Tissue engineering is revolutionizing urology by providing innovative methods for repairing and reconstructing the urinary system. This multidisciplinary approach combines biology, materials science, and clinical medicine to create functional tissue …
The article discusses the current landscape of stem cell therapy research, particularly its application in treating osteoarthritis (OA), a degenerative joint condition. It highlights a significant increase in publications and research focusing on …
The article discusses the role of Pioglitazone in regulating chondrocyte metabolism, highlighting its therapeutic potential for osteoarthritis (OA). Pioglitazone activates PPAR-γ, enhancing glucose uptake and glycolysis in chondrocytes, which helps …
The article discusses the significant role of synthetic nanopillars in bone regeneration, highlighting their ability to enhance osteoblast activity and promote osteointegration, particularly for conditions like osteoporosis and fractures. Traditional …
Arthritis is a widespread condition affecting over 350 million people globally, primarily osteoarthritis and rheumatoid arthritis. It causes joint inflammation, pain, and stiffness, leading to chronic disability and economic burdens on healthcare …
The article discusses the crucial role of effective antimicrobial agents in dentistry, particularly in the context of rising antibiotic resistance. With conventional antibiotics becoming less effective against resistant bacteria like Staphylococcus …
The article discusses tooth wear, a condition caused by mechanical and chemical factors leading to the loss of dental hard tissues. It identifies three primary forms of tooth wear: attrition, erosion, and abrasion, each necessitating specific …
The article discusses the critical role of angiogenesis in diabetic wound healing, particularly concerning diabetic foot ulcers that affect about 25% of diabetic patients. Angiogenesis, the formation of new blood vessels, is essential for supplying …
Rotator cuff injuries are common among individuals over 40, with surgical retear rates remaining high due to challenges in tendon-bone healing, which often results in scar tissue formation instead of restoring the native structure. Decellularized …
The article discusses the emerging link between oral microbiota, particularly dysbiosis caused by periodontal disease, and the formation and rupture of intracranial aneurysms (IAs). It highlights that oral pathogens, especially Porphyromonas …
The article discusses the increasing use of medical devices and biomaterials in healthcare, emphasizing the importance of materiovigilance in ensuring patient safety. Materiovigilance involves systematically monitoring and analyzing adverse effects …
Dental plaque is a colorless, sticky film of bacteria that forms on teeth and gums, primarily composed of bacteria, salivary proteins, food debris, and an extracellular matrix. If not removed, plaque can harden into tartar, leading to cavities and …
