The article discusses the impact of Acute Hepatic Porphyria (AHP) on resistant hypertension, noting that many patients with undiagnosed AHP may experience hypertension due to neurovisceral attacks and dysautonomia. A significant prevalence of …
Hemophilia is a rare, inherited blood disorder characterized by deficiencies in clotting factors, primarily factor VIII (Hemophilia A) and factor IX (Hemophilia B), leading to prolonged bleeding. There are three types of hemophilia: A, B, and C, with …
The article provides an overview of hemophilia, a genetic bleeding disorder primarily affecting males, while females can be carriers without symptoms. It explains the genetic inheritance of hemophilia, which follows an X-linked recessive pattern, and …
Reactive thrombocytosis is a condition where the body produces an excess of platelets in response to external stimuli such as infections, injuries, or other medical conditions. This differs from primary thrombocytosis, which is due to intrinsic bone …
Wiskott-Aldrich Syndrome (WAS) is a rare X-linked genetic disorder characterized by a triad of symptoms: eczema, recurrent infections, and thrombocytopenia (low platelet count). It results from mutations in the WAS gene, which impairs the immune …
Thrombocytopenia is a medical condition characterized by abnormally low platelet counts in the blood, leading to increased risks of bleeding and bruising. Normal platelet levels range from 150,000 to 450,000 per microliter, with severe …
Hemlibra is a groundbreaking treatment for hemophilia A, especially for patients with inhibitors to traditional clotting factor therapies. It functions by bridging activated factor IX and factor X, enhancing the clotting process and significantly …
The article discusses thrombocytopenia during pregnancy, which can stem from physiological changes, medical conditions, or medications. It highlights that while mild thrombocytopenia is common (affecting 7% to 10% of pregnant women), severe cases can …
Arteriovenous malformations (AVMs) are rare vascular abnormalities characterized by abnormal connections between arteries and veins, bypassing the capillary bed, which can lead to serious complications like hemorrhages or strokes, particularly when …
Hereditary Hemorrhagic Telangiectasia (HHT), or Osler-Weber-Rendu syndrome, is a genetic disorder marked by abnormal blood vessel growth, leading to arteriovenous malformations (AVMs) and recurrent bleeding, primarily due to mutations in the ENG or …
Thrombocytopenia is characterized by a platelet count below 150,000 per microliter and is categorized into mild, moderate, and severe levels. Its causes include bone marrow disorders, platelet destruction, and sequestration in the spleen, with …
The article defines Benign Hereditary Telangiectasia (BHT) as a genetic condition manifesting as small, visible dilated blood vessels, commonly referred to as spider veins, primarily affecting the skin around the lips and face. It contrasts BHT with …
The article “Exploring Hemophilia Complications: What You Need to Know” discusses hemophilia, a genetic bleeding disorder resulting from a deficiency in clotting factors, primarily factor VIII (Hemophilia A) and factor IX (Hemophilia B). …
The article “Understanding Clotting Factors: The Building Blocks of Hemostasis” explains the critical role of blood clotting factors in hemostasis, the process that prevents and stops bleeding. These proteins, produced mainly in the …
Hereditary hemorrhagic telangiectasia (HHT), also known as Rendu-Osler-Weber syndrome, is a genetic disorder marked by abnormal blood vessel formation, primarily affecting small capillaries, leading to easy bleeding. Common symptoms include recurrent …
Hemophilia is a rare inherited bleeding disorder caused by deficiencies in specific blood clotting factors, primarily factor VIII (Hemophilia A) and factor IX (Hemophilia B). Its severity is linked to the level of these factors in the blood, with …
Hereditary Hemorrhagic Telangiectasia (HHT), or Osler-Weber-Rendu syndrome, is a rare genetic disorder marked by abnormal blood vessel formation due to mutations in genes such as ENG and ACVRL1. Affecting roughly 1 in 5,000 individuals globally, HHT …
Thrombocytopenia is a condition marked by a low platelet count, essential for blood clotting, with normal levels ranging from 150,000 to 450,000 platelets per microliter. Symptoms arise as counts decrease, particularly below 150,000, with severe …
Bernard-Soulier syndrome (BSS) is a rare inherited bleeding disorder characterized by low platelet counts (thrombocytopenia) and the presence of abnormally large platelets (macrothrombocytes), leading to symptoms such as easy bruising, prolonged …
Thrombocytopenia is a condition characterized by a low platelet count in the blood, critical for normal clotting, with counts below 150,000/μL considered thrombocytopenic. The condition can arise from decreased production in the bone marrow, …
Hemophilia is an inherited bleeding disorder primarily affecting males, caused by deficiencies in clotting factors VIII (Hemophilia A) or IX (Hemophilia B). Severity varies, with severe cases leading to spontaneous bleeding episodes that can cause …
The article discusses Hemophilia A, the most common form of the bleeding disorder, which affects about 1 in 5,617 male births in the U.S. It results from a deficiency of clotting factor VIII, located on the X chromosome, making it an X-linked …
Hypercoagulation, or thrombophilia, is a disorder characterized by excessive blood clotting, increasing the risk of thrombosis-related complications such as deep vein thrombosis (DVT), pulmonary embolism, stroke, and heart attack. This condition can …
