Kawasaki Disease (KD) is an acute vasculitis primarily affecting children under five, marked by prolonged fever and systemic inflammation. While KD is usually self-limiting, it can lead to serious cardiovascular issues, particularly coronary artery …
Kalbitor, or ecallantide, is an innovative treatment for acute attacks of Hereditary Angioedema (HAE), a genetic disorder that causes severe swelling. It works by inhibiting plasma kallikrein, which reduces bradykinin levels, responsible for the …
Berinert is a human plasma-derived C1 esterase inhibitor used to treat acute attacks of hereditary angioedema (HAE). It helps regulate the immune system by counteracting the excessive production of bradykinin, which causes swelling. The recommended …
Haegarda is a medication used to prevent Hereditary Angioedema (HAE) attacks. Common mild side effects include injection site reactions (31% of patients), dizziness (5%), and upper respiratory symptoms (11%). Serious side effects, though rarer, can …
Kalbitor, or ecallantide, is a medication used to treat acute attacks of hereditary angioedema (HAE), a condition caused by mutations in the C1-esterase inhibitor gene. It works by inhibiting plasma kallikrein, blocking the inflammation cascade …
Firazyr (icatibant) is a synthetic decapeptide treatment for hereditary angioedema (HAE), functioning as a bradykinin B2 receptor antagonist to alleviate severe swelling episodes. Administered via subcutaneous injection, it is effective in managing …
Firazyr is a targeted treatment for acute attacks of hereditary angioedema (HAE), functioning by blocking bradykinin, a peptide that leads to swelling. Its subcutaneous administration allows patients to self-manage their symptoms, enhancing their …
The article “Understanding the Cost Structure of Berinert: What Patients Need to Know” discusses the financial implications of Berinert, a biologic medication used to treat hereditary angioedema (HAE). The cost per dose ranges from $2,000 …
Ruconest is an injectable medication used for treating acute attacks of hereditary angioedema (HAE). It comes in a lyophilized form, containing 2200 units of conestat alfa, and must be reconstituted with sterile water before intravenous …
Haegarda is a medication used to prevent hereditary angioedema (HAE) attacks, available in two powder forms (2,000 or 3,000 units) that require reconstitution with sterile water. The recommended dosage is 60 units per kilogram, administered …
Takhzyro (lanadelumab) is a monoclonal antibody that inhibits plasma kallikrein, effectively treating hereditary angioedema (HAE) by reducing bradykinin production and preventing swelling attacks. The typical starting dosage for patients aged 12 and …
Empaveli (empagliflozin) is a medication used to treat paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disorder that destroys red blood cells and can lead to serious anemia. It acts as a complement inhibitor to improve patients’ quality …
The article discusses Firazyr (icatibant), a revolutionary treatment for hereditary angioedema (HAE), a genetic condition that causes severe swelling due to an imbalance of the C1 inhibitor protein. Firazyr is a bradykinin B2 receptor antagonist that …
