The article discusses the identification of key proviral host factors that significantly influence SARS-CoV-2 replication. A total of 253 host factors were screened, highlighting several critical for viral entry, replication, and egress, including …
The article discusses the critical role of host factors in the replication of RNA viruses, particularly SARS-CoV-2. These host factors, which can either promote or inhibit viral replication, are essential for understanding viral life cycles and …
Candidemia, a bloodstream infection caused by Candida species, poses a significant clinical challenge, especially in immunocompromised patients and those with indwelling catheters. The condition has seen an increase in incidence and can result in …
Viral infections and non-communicable diseases (NCDs) pose significant public health challenges globally. Viral infections, such as influenza and HIV, can lead to acute health crises, particularly in vulnerable populations like the elderly. NCDs, …
The article discusses Severe Fever with Thrombocytopenia Syndrome (SFTS), a viral illness primarily transmitted through tick bites and contact with infected bodily fluids. SFTS manifests with symptoms like fever, thrombocytopenia, and leukopenia, …
The article discusses Post-Acute Sequelae of SARS-CoV-2 (PASC), highlighting its common symptoms such as fatigue, cognitive impairment, neurological issues, cardiovascular symptoms, and psychological effects. It emphasizes the potential of Dual …
The article discusses how natural compounds inhibit viral replication and infection through direct antiviral effects and modulation of the host immune response. It highlights Malabaricone C, derived from nutmeg, as a potent inhibitor of SARS-CoV-2, …
The article provides an overview of SARS-CoV-2 and its immune response, highlighting its significant impact on global health due to the COVID-19 pandemic. SARS-CoV-2 primarily infects the respiratory tract but can also affect multiple organ systems, …
The article discusses the role of Thymus and activation-regulated chemokine (TARC), also known as CCL17, as a predictive biomarker for COVID-19 severity, particularly during the Omicron variant period. Research indicates that elevated TARC levels …
The immune response to SARS-CoV-2 infection involves a complex interaction between innate and adaptive immunity. Initially, the virus triggers an innate immune response through pattern recognition receptors, leading to the production of type I …
The article provides an overview of SARS-CoV-2’s viral replication and mutation rates, highlighting its high mutation rate due to the instability of its RNA genetic material. The virus enters host cells through the spike protein binding to the …
