Imfinzi (durvalumab) is an intravenous immunotherapy used primarily for advanced non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). It is administered in cycles of 14 or 28 days, with each infusion lasting about one hour, and …
Dasatinib, known as Sprycel, is a powerful tyrosine kinase inhibitor used primarily to treat chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). It targets the BCR-ABL fusion protein, disrupting …
Nerlynx (neratinib) is an oral tyrosine kinase inhibitor that targets the HER2 receptor, essential for treating HER2-positive breast cancer, especially in patients who have previously undergone trastuzumab therapy. By irreversibly inhibiting HER2 and …
Pazopanib, marketed as Votrient, is a targeted therapy used primarily for advanced kidney cancer, specifically renal cell carcinoma (RCC). It functions as a multi-kinase inhibitor, blocking tyrosine kinases that promote cancer cell growth and …
Cyclosporine is a powerful immunosuppressant crucial for preventing organ rejection in transplants and managing autoimmune diseases like rheumatoid arthritis and psoriasis. Isolated from the fungus Tolypocladium inflatum in the 1970s, it selectively …
Tagrisso (osimertinib) is a targeted therapy for non-small cell lung cancer (NSCLC) with specific mutations in the epidermal growth factor receptor (EGFR) gene. As a third-generation tyrosine kinase inhibitor (TKI), it effectively addresses the T790M …
Atezolizumab, branded as Tecentriq, is an innovative immunotherapy drug primarily used to treat non-small cell lung cancer (NSCLC) and urothelial carcinoma. It functions by inhibiting the PD-L1 protein, which allows cancer cells to evade the immune …
Zejula (niraparib) is an oral PARP inhibitor used for treating recurrent ovarian cancer, particularly in patients previously treated with platinum-based chemotherapy. It is particularly effective for those with BRCA1 and BRCA2 mutations, as it …
Chemotherapy is a vital treatment for cancer, especially for non-small cell lung cancer (NSCLC), which accounts for about 85% of lung cancer cases. It utilizes cytotoxic drugs to target and destroy rapidly dividing cancer cells by disrupting their …
The article emphasizes the significance of being aware of the side effects associated with Loqtorzi, a medication for non-small cell lung cancer (NSCLC). Side effects can vary among patients and may include fatigue, nausea, liver function changes, …
Ceritinib, known as Zykadia, is a targeted therapy for advanced non-small cell lung cancer (NSCLC) that is positive for the anaplastic lymphoma kinase (ALK) gene. As a tyrosine kinase inhibitor, it blocks the ALK enzyme, crucial for cancer cell …
Retevmo (selpercatinib) is a targeted therapy approved by the FDA for treating advanced non-small cell lung cancer (NSCLC) and medullary thyroid cancer with RET gene alterations. It works by inhibiting abnormal RET proteins that promote tumor growth, …
Inlyta (axitinib) is a targeted therapy for advanced renal cell carcinoma (RCC), classified as a tyrosine kinase inhibitor (TKI) that blocks vascular endothelial growth factor receptors (VEGFRs) to inhibit tumor growth and angiogenesis. Approved by …
Sunitinib, known by the brand name Sutent, is a targeted cancer therapy effective in treating advanced renal cell carcinoma (RCC), gastrointestinal stromal tumors (GIST) resistant to imatinib, and pancreatic neuroendocrine tumors (PNET). As a protein …
Nexavar, or sorafenib, is a targeted therapy primarily used for treating renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC). As a multi-kinase inhibitor, it blocks receptor tyrosine kinases involved in tumor growth and angiogenesis, …
Vitrakvi (larotrectinib) is a tumor-agnostic targeted therapy approved by the FDA in 2018 for solid tumors with abnormal NTRK gene fusions. Its effectiveness is determined by specific genetic markers rather than tumor location. The recommended dosage …
Mektovi (binimetinib) is a targeted cancer therapy primarily used for melanoma patients, functioning as a MEK inhibitor to disrupt the MAPK signaling pathway, which is vital for cancer cell growth. It is often combined with Braftovi (encorafenib) to …
Keytruda, a cancer immunotherapy, works by blocking the PD-1 receptor, enhancing T cell activation and promoting anti-tumor immunity. This mechanism allows T cells to recognize and attack cancer cells more effectively. The effectiveness of Keytruda …
Gleevec, a tyrosine kinase inhibitor approved by the FDA, plays a crucial role in treating various cancers, including Philadelphia chromosome-positive chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GIST). Clinical studies show …
Augtyro, or repotrectinib, is a novel medication designed for treating non-small cell lung cancer (NSCLC) with ROS1 gene fusions, particularly beneficial for patients whose cancer has progressed after previous therapies. It works by inhibiting …
Poteligeo (mogamulizumab) is a monoclonal antibody targeting CCR4, primarily used for treating relapsed or refractory mycosis fungoides (MF) and Sézary syndrome, types of cutaneous T-cell lymphoma (CTCL). It recruits immune effector cells to …
Cabozantinib, marketed as Cabometyx, is a targeted therapy that inhibits key receptor tyrosine kinases (RTKs) like VEGFR, MET, and AXL, which are crucial for tumor growth and metastasis. It is indicated for advanced renal cell carcinoma (RCC) after …
Gilotrif, or afatinib, is a targeted therapy for non-small cell lung cancer (NSCLC) that specifically inhibits the epidermal growth factor receptor (EGFR), making it effective for patients with certain genetic mutations. Classified as a tyrosine …
Mekinist, or trametinib, is a MEK inhibitor used primarily to treat advanced melanoma, especially in patients with specific BRAF mutations (V600E or V600K). Approved by the FDA in 2013, it serves as a systemic oral therapy for patients with …
Imbruvica (ibrutinib) is a targeted cancer therapy that acts as a Bruton’s tyrosine kinase (BTK) inhibitor, primarily used to treat blood cancers like mantle cell lymphoma, chronic lymphocytic leukemia (CLL), and Waldenstrom’s …
