Bone regeneration is an essential focus in tissue engineering, particularly for patients with bone loss due to injuries, tumors, or diseases. Traditional repair methods like autografts have limitations, prompting research into advanced biomaterials …
Osteoarthritis (OA) is a degenerative joint disease impacting millions globally, particularly affecting individuals over 60 years old. It leads to chronic pain, stiffness, and functional impairment, significantly reducing quality of life. The disease …
Intervertebral disc degeneration (IVDD) is a prevalent condition that affects many individuals, leading to significant lower back pain. Characterized by the deterioration of intervertebral discs, IVDD results in reduced disc height and changes in …
Copper is a vital trace element that significantly contributes to bone health through collagen synthesis, osteoblast proliferation, and bone metabolism regulation. It also has antimicrobial properties that help prevent infections related to bone …
Knee osteoarthritis (KOA) is a common degenerative joint disease that leads to pain, stiffness, and decreased mobility, significantly affecting the quality of life, particularly in the elderly. Traditional treatments include non-steroidal …
The article discusses the significant role of mitogen-activated protein kinase (MAPK) signaling pathways, particularly ERK1/2 and p38 MAPK, in the osteogenic differentiation of periodontal ligament stem cells (PDLSCs). These pathways are activated by …
The article discusses several recent advancements in healthcare, focusing on innovative technologies and methodologies for improving health outcomes. Notably, wearable devices for opioid overdose detection have been developed to monitor vital signs …
Tissue engineering is revolutionizing urology by providing innovative methods for repairing and reconstructing the urinary system. This multidisciplinary approach combines biology, materials science, and clinical medicine to create functional tissue …
The article discusses the current landscape of stem cell therapy research, particularly its application in treating osteoarthritis (OA), a degenerative joint condition. It highlights a significant increase in publications and research focusing on …
The article discusses the role of Pioglitazone in regulating chondrocyte metabolism, highlighting its therapeutic potential for osteoarthritis (OA). Pioglitazone activates PPAR-γ, enhancing glucose uptake and glycolysis in chondrocytes, which helps …
The article discusses the significant role of synthetic nanopillars in bone regeneration, highlighting their ability to enhance osteoblast activity and promote osteointegration, particularly for conditions like osteoporosis and fractures. Traditional …
Arthritis is a widespread condition affecting over 350 million people globally, primarily osteoarthritis and rheumatoid arthritis. It causes joint inflammation, pain, and stiffness, leading to chronic disability and economic burdens on healthcare …
Rotator cuff injuries are common among individuals over 40, with surgical retear rates remaining high due to challenges in tendon-bone healing, which often results in scar tissue formation instead of restoring the native structure. Decellularized …
